Andrea Borghini received his master's degree in Biological Science (summa cum laude) from the University of Pisa in 2011. He obtained a 2nd level Master degree in Nutrition in 2012. Currently, he is a PhD student in Molecular Medicine at the University of Siena. The main interest of his PhD program concerns the identification of cardiovascular effects of low dose exposure to medical ionizing radiation. He is also involved in research projects aimed to study the genetic component of cardiovascular disease, including the understanding on how genes interact with environmental risk factors to cause disease.
1.Borghini A, Gianicolo EA, Andreassi MG. Usefulness of biomarkers as intermediate endpoints in health risks posed by occupational lead exposure. Int J Occup Med Environ Health 2016; 29:1-12.
2.Vecoli C, Borghini A, Foffa I, Ait Ali L, Picano E, Andreassi MG. Leukocyte telomere shortening in grown-up patients with congenital heart disease . Int J Cardiol 2016; 204:17-22.
3.Mrakic-Sposta S, Gussoni M, Moretti S, Pratali L, Giardini G, Tacchini P, Dellanoce C, Tonacci A, Mastorci F, Borghini A, Montorsi M, Vezzoli A. Effects of Mountain Ultra-Marathon Running on ROS Production and Oxidative Damage by Micro-Invasive Analytic Techniques. PLoS One 2015; 10:e0141780.
4.Borghini A, Tonacci A, Mastorci F, Mercuri A, Mrakic-Sposta S, Moretti S, Andreassi MG, Pratali L. Chronic and acute effects of endurance training on telomere length. Mutagenesis 2015; 30:711-6.
5.Andreassi MG, Piccaluga E, Gargani L, Sabatino L, Borghini A, Faita F, Bruno RM, Padovani R, Guagliumi G, Picano E. Subclinical carotid atherosclerosis and early vascular aging from long-term low-dose ionizing radiation exposure: a genetic, telomere, and vascular ultrasound study in cardiac catheterization laboratory staff. JACC Cardiovasc Interv 2015; 8:616-27.
6.Sabina S, Vecoli C, Borghini A, Guarino R, Andreassi MG. Analysis of miRNAs Targeting 3'UTR of H2AFX Gene: a General in Silico Approach. Microrna 2015; 4:41-9.
7.Borghini A, Mercuri A, Turchi S, Chiesa MR, Piccaluga E, Andreassi MG. Increased circulating cell-free DNA levels and mtDNA fragments in interventional cardiologists occupationally exposed to low-levels of ionizing radiation. Environ Mol Mutagen 2015; 56:293-300.
8.Borghini A, Andreassi MG. Effetti patologici dell’esposizione a radiazioni ionizzanti. Il Giornale Italiano di Cardiologia Invasiva 2014;3.
9.Bustaffa E, Minichilli F, Andreassi MG, Carone S, Coi A, Cori L, Faita F, Faita F, Grecchi S, Minoia C, Ronchi A, Scovassi I, Sicari R, Stea F, Bianchi F; SEpiAs Working Group. Studies on markers of exposure and early effect in areas with arsenic pollution: methods and results of the project SEpiAs. Epidemiological surveillance in areas with environmental pollution by natural or anthropogenic arsenic. Epidemiol Prev 2014; 38 (3-4 Suppl 1): 27-94.
10.Borghini A, Vecoli C, Mercuri A, Petruzzelli MF, D’Errico MP, Portaluri M, Andreassi MG. Genetic risk score and acute skin toxicity after breast radiation therapy. Cancer Biother Radiopharm 2014; 29:267-72.
11.Borghini A, Sbrana S, Vecoli C, Mercuri A, Turchi S, Carpeggiani C, L’Abbate A, Andreassi MG. SDF1-3′A polymorphism is associated with decreased risk of MI and early endothelial disturbance. J Cardiovasc Med 2014; 15:710-6.
12.Borghini A, Cervelli T, Galli A, Andreassi MG. DNA modifications in atherosclerosis: From the past to the future. Atheroclerosis 2013; 230:202-209.
13.Borghini A, Gianicolo EA, Picano E, Andreassi MG. Ionizing radiation and atherosclerosis: Current knowledge and future challenges. Atherosclerosis 2013; 230:40-7.
14.Tonacci A*, Borghini A*, Mercuri A, Pioggia G, Andreassi MG. Brain-derived neurotrophiv factor (Val66Met) polymorphism and olfactory ability in young adults. J Biomed Sci. 2013; 20:57* Equal contributors.
15.Labate L, Andreassi MG, Baffigi F, Basta G, Bizzarri R, Borghini A, Candiano GC, Casarino C, Cresci M, Di Martino F, Fulgentini L, Ghetti F, Gilardi MC, Giulietti A, Koester P, Lenci F, Levato T, Oishi Y, Russo G, Sgarbossa A, Traino C, Gizzi LA. Small-scale laser based electron accelerators for biology and medicine: a comparative study of the biological effectiveness. SPIE Proceedings 2013; volume 8779.
16.Mercuri A, Turchi S, Borghini A, Chiesa MR, Lazzerini G, Musacchio L, Zirilli O, Andreassi MG. Nitrogen biobank for cardiovascular research. Curr Cardiol Rev 2013; 9:253-9.
17.Sabatino L, Botto N, Borghini A, Turchi S, Andreassi MG. Development of a new multiplex quantitative real-time PCR assay for the detection of the mtDNA (4977) deletion in coronary artery disease patients: a link with telomere shortening. Environ Mol Mutagen 2013; 54:299-3077.
18.Cervelli T, Borghini A, Galli A, Andreassi MG. DNA damage and repair in vascular disease: current insights and future perspectives. Int J Mol Sci 2012; 13: 16929-44.
19.Andreassi MG, Laghi Pasini F, Picano E, Capecchi PL, Pompella G, Foffa I, Borghini A, Sicari R. Adenosine A2(A) receptor gene polymorphism (1976C>T) affects coronary flow reserve response during vasodilator stress testing in patients with non ischemic-dilated cardiomyopathy. Pharmacogenet Genomics 2011; 21:469-75.
Il giorno 17 febbraio 2016 il dott. BORGHINI ha conseguito il titolo di Dottore di Ricerca in Medicina Molecolare con una tesi dal titolo “Early biomarkers of radiation-induced cardiovascular disease from chronic occupational exposure in catheterization laboratory”