Silvestri Roberto

Breve curriculum vitae
EDUCATION 
 

01/2017 – current:  PhD student in Molecular Medicine, University of Siena, Siena (Italy); 

10/2014-04/2017: MSc Molecular and Cellular Biology, University of Pisa, Pisa (Italy); “Analysis of the regulatory mechanisms underlying MSLN gene expression” 

10/2001-06/2014: BSc Biological and Molecular Sciences, University of Pisa, Pisa (Italy); “Identification of miRNAs affecting MSLN gene expression” 

 
 
RESEARCH EXPERIENCE 
 

08/2017- 10/2017:  Internship at the University of Pisa ,Prof. Stefano Landi, University of Pisa, Pisa (Italy).Study of circulating free DNA in patients affected by malignant pleural  mesothelioma 

05/2017-07/2017: Internship at the Open University.Dott. Francesco Crea, Dott. Martin Bootman, Open University, Milton Keynes (United Kingdom), Role of T-type calcium channels in neuroendocrine prostate cancer 

 
Pubblicazioni e abstracts
PUBLICATIONS 
 
A common polymorphism within MSLN affects miR-611 binding site and soluble mesothelin levels in healthy people. Journal of Thoracic Oncology, November 2014; 9(11):1662-8. doi:10.1097/JTO.0000000000000322. 
 
Mesothelin promoter variants are associated with increased Soluble-Mesothelin related Peptide (SMRP) levels in asbestos-exposed individuals. Occupational and Enviromental, June 2017; 74(6):456-463. doi: 10.1136/oemed-2016-104024 
 
T-type calcium channels drive the proliferation of androgen-receptor negative prostate cancer cells. Prostate, 23 July 2019; doi: 10.1002/pros.23879